In March, a journal article on NMN by Dr Brad McEwen PhD was published, titled “A Spotlight on Nicotinamide Mononucleotide (NMN)”. It was published in the peer-reviewed journal Australasian Journal of Natural Medicine.
This article discussed the preclinical research of NMN, including enhancing NAD+ biosynthesis, increasing intracellular NAD+ levels, and improving mitochondrial bioenergetics, cellular energy production, glucose and lipid metabolism, endothelial function, and insulin sensitivity. Additional mechanisms include activation of sirtuin pathways, the stimulation of autophagy, and reductions in oxidative stress and inflammation.
The article also discussed how NMN supplementation has led to improvements in arterial stiffness, lipid profiles, blood pressure, aerobic capacity, muscle insulin sensitivity, motor function, walking performance, sleep quality, and health-related quality of life.